Moderate alcohol is generally acceptable, but keep it sensible while you settle into treatment. Alcohol can irritate the stomach and may worsen nausea or reflux during dose increases. If you have diabetes or take medicines that can lower blood sugar, be extra cautious with alcohol and discuss safe limits with your team. Why alcohol and Wegovy can interact Wegovy (semaglutide) works by slowing how quickly food leaves the stomach, which is part of why people often feel fuller f