For kidney or liver issues, the dose ladder is usually the same, but clinicians monitor more closely. No routine dose adjustment is needed for mild-to-moderate impairment, yet dehydration from nausea or vomiting can stress the kidneys, so hydration and slower titration matter. In severe impairment or if labs are changing, prescribers may pause or hold at a lower step and review more frequently. Always flag any new swelling, dramatic fatigue, very dark urine, or reduced urine

Moderate alcohol is generally acceptable, but keep it sensible while you settle into treatment. Alcohol can irritate the stomach and may worsen nausea or reflux during dose increases. If you have diabetes or take medicines that can lower blood sugar, be extra cautious with alcohol and discuss safe limits with your team. Why alcohol and Wegovy can interact Wegovy (semaglutide) works by slowing how quickly food leaves the stomach, which is part of why people often feel fuller f