For kidney or liver issues, the dose ladder is usually the same, but clinicians monitor more closely. No routine dose adjustment is needed for mild-to-moderate impairment, yet dehydration from nausea or vomiting can stress the kidneys, so hydration and slower titration matter. In severe impairment or if labs are changing, prescribers may pause or hold at a lower step and review more frequently. Always flag any new swelling, dramatic fatigue, very dark urine, or reduced urine

Alcohol doesn’t change the prescribed dose, but it can aggravate stomach symptoms and undermine appetite cues, especially during dose...

Phentermine can produce modest, short-term weight loss, but it is not licensed in the UK for obesity treatment. In contrast, semaglutide...

Yes, Wegovy and metformin are often used together in people with type 2 diabetes, and no special dose adjustment is typically required. They work differently: Wegovy (a GLP-1 receptor agonist) reduces appetite, slows stomach emptying, and boosts insulin release, while metformin mainly reduces glucose production in the liver and improves insulin sensitivity. Why these medicines are combined Doctors frequently prescribe Wegovy (semaglutide) alongside metformin, particularly in

There are no strict dietary restrictions, but simple tweaks help you feel better on treatment. Smaller portions, slower eating, and higher-protein meals reduce nausea and keep you fuller for longer. Early on, many people do better with lighter foods and by limiting very rich, spicy, or greasy dishes. Hydration matters — sip water regularly, and consider a little extra salt if you’ve cut back on processed foods and feel light-headed. Alcohol is best kept moderate, especially w

Wegovy does not “boost metabolism” in the thermogenic sense; its primary action is appetite regulation and reduced intake. As weight decreases, resting energy expenditure typically falls a little — that’s a normal adaptation seen with any weight loss. The meaningful advantage here is reduced hunger and cravings, which makes long-term behaviour change more realistic. Improvements in metabolic risk markers are observed in many users, but they stem from weight reduction and bett

Wegovy alters appetite and satiety by activating GLP-1 receptors on neurons that signal “you’ve had enough,” while dialing down circuits that push “keep eating.” This reduces the intensity and frequency of cravings, especially for highly palatable foods. People often describe quieter “food noise,” easier portion control, and feeling satisfied sooner without forcing it. How GLP-1 receptors affect appetite Wegovy’s active ingredient, semaglutide, works by mimicking the hormone

For long-term weight loss, sustained treatment in structured services has shown meaningful average reductions, with plateaus that are...

The medicine is intended to sit alongside a reduced-calorie diet and regular movement, not replace them. People usually find it easier to meet protein targets, shrink portions, and cut between-meal snacking when appetite is quieter. Light-to-moderate activity protects muscle while weight comes down, and small daily habits (steps, resistance bands at home, shorter eating windows that suit you) compound gains without feeling punitive. UK services will tailor this mix and adjust

The first few weeks focus on getting used to weekly injections and allowing your body to adapt at a low dose. Common early effects...

Appetite suppression with semaglutide comes from activating GLP-1 receptors in brain regions that govern hunger and satisfaction,...

The primary target is the GLP-1 receptor, found in brain regions that regulate hunger and satiety and in the gut’s signalling pathways....

Some people notice appetite changes within the first few weeks, but the medicine is introduced gradually to improve tolerability, so its...

The core benefit for weight loss is better appetite control: less urge to snack, fewer intrusive cravings, and earlier fullness at meals....

If you've ever felt a bit stuck trying to shift extra weight, you’re certainly not alone. Many of us reach a point where we think,...

You know that feeling when you’re finally ready to make a real change — not just another start‑and‑stop attempt, but something that might...

Achieving a balanced body composition through building muscle and losing fat is a vital aspect of overall health and fitness. This journey not only enhances physical appearance but also bolsters strength, boosts metabolism, and improves mental well-being. Combining Wegovy, a weight management medication, with strength training emerges as a potent strategy to optimize results. Wegovy assists in weight loss, while strength training helps in preserving muscle mass and promoting

The journey to parenthood can be deeply fulfilling, but it often involves careful planning and considerations, especially when it comes...

Navigating the weight loss journey can be both challenging and rewarding, and nutrition plays a vital role in this process. For women...

Embarking on a weight loss journey can sometimes feel like navigating through a maze. Often, it’s not just about what we eat but also...