General Advice

Dietary habits do not affect how Wegovy is absorbed since it is injected under the skin. However, NHS advice suggests avoiding very rich or fatty meals during dose escalation, as these may worsen nausea. Many people find it helpful to eat smaller, protein-rich meals around injection day to support comfort. Staying well hydrated also reduces the risk of stomach upset in the first few months. Why food choices matter with Wegovy Although Wegovy (semaglutide) bypasses the digesti

Yes, a trained caregiver can give the injection. They should follow the same steps you were taught: new needle each time, flat contact...

Yes — rotate every week. You can stay within the same general area (e.g., abdomen) but move at least a finger-width or two from the...

Absolutely — do not self-adjust. Your prescriber will change the plan if you’re struggling with side effects, preparing for a procedure...

Yes. As the dose rises, appetite control generally strengthens, but gastro-intestinal side effects (nausea, reflux, constipation or...

The usual maximum recommended dose is 2.4 mg once weekly. Some people remain at 1.7 mg if that’s better tolerated; higher weekly doses...

Place used needles straight into a sharps container — never in household rubbish or recycling. Many pharmacies provide take-back schemes...

No — use abdomen, thigh, or upper arm only, into the fatty layer under the skin. Avoid veins, muscles, moles, scars, stretch marks, or...

Watch for persistent or worsening nausea, repeated vomiting, dizziness, or dehydration (very dark urine, feeling faint). Severe, constant...

Wegovy may be considered for adolescents in specialist services when strict criteria are met, but this is not the same as routine adult...

No — Wegovy is intended as a single weekly dose. Splitting or repeating injections can upset the dosing schedule and increase side-effect...

If a little fluid appears on the skin, it’s usually from the needle track rather than a full dose loss. As a rule, don’t inject an extra dose; note what happened and continue with your next scheduled injection. For clear device errors (pen not primed correctly, needle blocked, or you know the dose didn’t deliver), contact your pharmacist or clinic for specific advice before re-dosing. To prevent repeats, ensure the needle is new, the pen is pressed flat against the skin, and

Keep unopened pens in the refrigerator (2–8 °C) in their carton, away from the freezer compartment. For in-use pens, store below 30 °C, cap on, and note the 6-week in-use limit on the box so you don’t lose track. Don’t store with a needle attached, and keep all pens and sharps out of children’s reach. Why correct storage matters Wegovy is a protein-based medicine, and like other injectables, it is sensitive to changes in temperature, light, and handling. That means how you st

Yes. You can change to a new weekly day as long as at least 3 full days have passed since your last injection. Once you switch, keep using the new day each week. If you’re unsure about the timing, ask your clinic to help you plan the change. Why flexibility exists Wegovy is designed as a once-weekly injection, and the dosing rules were created with real life in mind. Few people manage a routine that never changes. Work patterns, holidays, travel, or family events can all inte

Any time of day works — morning or evening — because the weekly dose is designed to be flexible. Pick a time you can stick to, keep it the same each week, and set a reminder so doses aren’t missed. If your routine changes (shift work, travel), you can move the time as long as your weekly schedule stays consistent. A flexible schedule Wegovy is designed as a once-weekly injection, and its long half-life means the exact time of day does not affect how well it works. Whether you

In major STEP trials, Wegovy led to about 15% weight loss over 68 weeks. Contrave (called Mysimba in the UK) generally achieves around 6–9% across pivotal studies. This means semaglutide tends to provide greater weight reduction than naltrexone/bupropion combinations. Two very different medicines Although both Wegovy and Contrave are used for weight management, they belong to very different drug families and work in different ways. Wegovy contains semaglutide, a GLP-1 recepto

Wegovy contains semaglutide at a higher dose and is licensed for weight management, while Trulicity (dulaglutide) is prescribed for type 2 diabetes. Weight changes with dulaglutide are usually modest compared with the significant reductions seen in trials of semaglutide for obesity. Different active ingredients and purposes The first key difference is that Wegovy and Trulicity contain different GLP-1 receptor agonists. Wegovy delivers semaglutide at doses up to 2.4 mg weekly,

Use once weekly, same day each week, with or without food, alongside a reduced-calorie eating plan and regular activity. Keep hydrated,...

Standard UK instructions start at 0.25 mg once weekly and step up gradually to improve comfort and reduce tummy side effects. Starting at 0.5 mg is not the routine plan and tends to increase nausea for first-time GLP-1 users. If you’ve previously tolerated a GLP-1, your prescriber will still weigh the pros and cons before deviating from the usual start. Why titration matters Wegovy contains semaglutide, a GLP-1 receptor agonist that acts on appetite control centres in the bra

You can change your weekly injection day if needed, as long as there are at least 3 days (72 hours) between two doses. After switching, keep to the new weekly day going forward. For missed doses, the rule is different: if you are within 5 days, take it as soon as you remember; if it has been more than 5 days, skip it and take the next dose on your usual day. Why flexibility is built in Wegovy is prescribed as a once-weekly injection. The idea is to give people a medicine that