General Advice

There are no strict activities to avoid, but comfort improves if you skip very hot environments (saunas, hot tubs) and high-intensity core work for a few hours after injecting a tender area. If you feel queasy on escalation weeks, keep meals light, postpone vigorous workouts until later in the day, and limit alcohol. Don’t massage the injection site; a cool pack helps if it stings. If dizziness or reflux appears, avoid driving until you feel steady and speak with your team ab

Intermittent use isn’t recommended; Wegovy is designed for consistent weekly dosing. Stopping and starting can bring appetite surges and weight regain, and it complicates review criteria. If you need a pause (side effects, procedures, travel), agree a plan with your clinician so re-starting is safe and structured. Why Wegovy is designed for steady use Wegovy (semaglutide) works best when injected on a consistent weekly schedule. NICE TA875 and NHS England’s 2025 weight-manage

Prioritise protein at each meal, slow down eating, and include fibre-rich foods to support fullness. Keep daily steps and two short resistance sessions weekly to protect strength; limit alcohol and maintain good sleep to stabilise appetite signals. Plan hydrated, portion-aware days around your injection, and rotate injection sites. Small, repeatable routines beat perfection — your team will help tailor these to your life, and devolved-nation services may offer slightly differ

Yes — mild redness, itching, or small lumps can occur and usually settle. Rotate sites weekly to prevent lipohypertrophy (fatty thickening) and avoid injecting into scars, moles, or irritated skin. If you see persistent nodules, colour changes, warmth, or pain, switch location and ask your clinician to review technique and needle size. Why skin reactions happen Wegovy (semaglutide) is injected into the fatty layer under the skin (the subcutaneous tissue), where small local re

With illness or fever, focus on fluids, simple foods, and rest; if vomiting or dehydration is significant, contact your service before taking the next dose. For stomach bugs, clinicians often advise delaying until you’re tolerating fluids and food again. If you’re booked for procedures with sedation or anaesthesia, your team may adjust timing to reduce aspiration risk — always follow their specific instructions. Why illness matters for Wegovy dosing Short-term illness, such a

Some people report better sleep as late-night snacking eases and caffeine intake drops, while others notice temporary sleep disruption from nausea or reflux during dose increases. Practical tweaks help: avoid large meals close to bedtime, prop the upper body slightly if reflux flares, and keep evening alcohol modest. If sleep remains poor, your clinician can adjust titration pace and review other contributors (stress, screen time, other medicines). How Wegovy can influence sl

Yes — for older adults, start low, go slow, and protect muscle. Appetite reduction plus low protein can increase frailty risk, so set a protein target and add light resistance work if feasible. Review other medicines for dizziness or dehydration risk, and monitor renal function and blood pressure routinely. Services may schedule closer follow-up for people living with frailty or multiple conditions. Why Wegovy requires extra care in older adults Wegovy (semaglutide) can be us

Signs include no change in appetite, cravings as frequent as before, or weight not trending down across reviews despite steady use....

Contact your clinic or GP well before the final dose in your pen so there’s time to process repeats and navigate any supply constraints....

No — pregnancy and breastfeeding are not recommended with Wegovy. Women of child-bearing potential should use effective contraception and...

The pen is a multi-dose device containing several weekly doses at the same strength; the needle is single-use only and must be changed each injection. You don’t refill the pen, and you discard it when it’s empty or past the in-use window noted in the leaflet. Never share a pen with anyone else. Understanding the Wegovy pen design Wegovy (semaglutide) pens are pre-filled, multi-dose devices, meaning each contains several weekly doses of the same strength. NICE TA875, MHRA prod

Not at present — genetic or metabolic profiling isn’t used to set Wegovy doses in UK services. Dosing is “treat-to-tolerate” and...

No liquid is required — Wegovy is a subcutaneous injection, not a tablet. If you feel queasy, small sips of water or a ginger tea can...

Follow-up typically includes regular weight checks, symptom review, pulse and blood pressure, and a look at your food/activity plan. Many...

Yes — hold the pen at 90° to the skin and press flat so the needle enters the fatty layer, not muscle. If you’re very lean at the chosen...

Brief tingling or numbness can occur from needle irritation and usually fades quickly. Persistent numbness, marked pain, colour changes,...

For kidney or liver issues, the dose ladder is usually the same, but clinicians monitor more closely. No routine dose adjustment is needed for mild-to-moderate impairment, yet dehydration from nausea or vomiting can stress the kidneys, so hydration and slower titration matter. In severe impairment or if labs are changing, prescribers may pause or hold at a lower step and review more frequently. Always flag any new swelling, dramatic fatigue, very dark urine, or reduced urine

Ask for a medication summary with your start date, current dose, side-effect history, and any dose holds, and bring your pen and leaflet...

No — Wegovy uses fixed doses, not weight-based dosing. Heavier people don’t automatically receive higher doses, and lighter people aren’t...

Avoid stacking with another GLP-1 medicine unless advised by a specialist. If you use insulin or sulphonylureas, your prescriber may...