Weight Management

Place used needles straight into a sharps container — never in household rubbish or recycling. Many pharmacies provide take-back schemes...

No — use abdomen, thigh, or upper arm only, into the fatty layer under the skin. Avoid veins, muscles, moles, scars, stretch marks, or...

Wegovy may be considered for adolescents in specialist services when strict criteria are met, but this is not the same as routine adult...

Yes. You can change to a new weekly day as long as at least 3 full days have passed since your last injection. Once you switch, keep using the new day each week. If you’re unsure about the timing, ask your clinic to help you plan the change. Why flexibility exists Wegovy is designed as a once-weekly injection, and the dosing rules were created with real life in mind. Few people manage a routine that never changes. Work patterns, holidays, travel, or family events can all inte

Any time of day works — morning or evening — because the weekly dose is designed to be flexible. Pick a time you can stick to, keep it the same each week, and set a reminder so doses aren’t missed. If your routine changes (shift work, travel), you can move the time as long as your weekly schedule stays consistent. A flexible schedule Wegovy is designed as a once-weekly injection, and its long half-life means the exact time of day does not affect how well it works. Whether you

The vast majority of patients on Mounjaro currently pay for it privately but some patients can get it on the NHS...

Yes, Wegovy and metformin are often used together in people with type 2 diabetes, and no special dose adjustment is typically required. They work differently: Wegovy (a GLP-1 receptor agonist) reduces appetite, slows stomach emptying, and boosts insulin release, while metformin mainly reduces glucose production in the liver and improves insulin sensitivity. Why combination treatment is common Many people living with type 2 diabetes require more than one medicine to manage blo

In major STEP trials, Wegovy led to about 15% weight loss over 68 weeks. Contrave (called Mysimba in the UK) generally achieves around 6–9% across pivotal studies. This means semaglutide tends to provide greater weight reduction than naltrexone/bupropion combinations. Two very different medicines Although both Wegovy and Contrave are used for weight management, they belong to very different drug families and work in different ways. Wegovy contains semaglutide, a GLP-1 recepto

Wegovy contains semaglutide at a higher dose and is licensed for weight management, while Trulicity (dulaglutide) is prescribed for type 2 diabetes. Weight changes with dulaglutide are usually modest compared with the significant reductions seen in trials of semaglutide for obesity. Different active ingredients and purposes The first key difference is that Wegovy and Trulicity contain different GLP-1 receptor agonists. Wegovy delivers semaglutide at doses up to 2.4 mg weekly,

Use once weekly, same day each week, with or without food, alongside a reduced-calorie eating plan and regular activity. Keep hydrated,...

You can change your weekly injection day if needed, as long as there are at least 3 days (72 hours) between two doses. After switching, keep to the new weekly day going forward. For missed doses, the rule is different: if you are within 5 days, take it as soon as you remember; if it has been more than 5 days, skip it and take the next dose on your usual day. Why flexibility is built in Wegovy is prescribed as a once-weekly injection. The idea is to give people a medicine that

Recommended sites are the abdomen, thigh, or upper arm. Rotate sites each week to reduce local irritation, and avoid areas that are tender, bruised, scarred, or inflamed. If a spot stings or looks red after, switch to a different area next time and mention it at your review. NHS training stresses that choosing the right location improves comfort and consistency over the long term. Why injection site matters Wegovy is given subcutaneously, meaning the medicine needs to sit in

Wegovy has been tested in large clinical trials and shown to deliver sustained, clinically meaningful weight loss. Over-the-counter supplements rarely have robust evidence and typically produce little to no lasting effect, so the gap in proven effectiveness is significant. What makes Wegovy different Wegovy contains semaglutide, a GLP-1 receptor agonist that has been through rigorous clinical trials involving thousands of participants worldwide. The STEP programme of studies

Yes, trial evidence shows that Wegovy works best when combined with healthy eating and physical activity, leading to average weight losses of around 15%. Saxenda and Trulicity also perform better when paired with lifestyle support, but semaglutide at the doses used in Wegovy generally results in greater overall reductions. Why lifestyle support matters No weight-loss medicine is intended to work on its own. NICE guidance makes clear that drugs such as Wegovy, Saxenda, and Tru

Yes — trials show Wegovy users lose more weight earlier than with Saxenda, thanks to its stronger appetite effect and weekly dosing. That said, both require steady use over months for results to build. The two medicines at a glance Wegovy and Saxenda belong to the same family of medicines, GLP-1 receptor agonists. They help people feel fuller sooner, reduce appetite, and support healthier eating. The difference lies in the active ingredient and how they are dosed: Wegovy cont

Wegovy mimics the hormone GLP-1, acting on the brain to reduce appetite and slow digestion. Contrave (naltrexone/bupropion) affects brain reward and craving pathways, which can reduce emotional eating but doesn’t directly target satiety hormones. How Wegovy works Wegovy (semaglutide 2.4 mg weekly) is a GLP-1 receptor agonist. It mimics a natural gut hormone called GLP-1, which signals to the brain that you are full, slows down stomach emptying, and enhances insulin release wh

Both Wegovy (semaglutide 2.4 mg) and Trulicity (dulaglutide) improve blood sugar, but semaglutide generally produces greater reductions in HbA1c and body weight. NICE recommends semaglutide more widely for people needing weight-focused management. Two GLP-1 medicines, one key difference Wegovy and Trulicity both belong to the GLP-1 receptor agonist family of medicines. They mimic the hormone GLP-1, which reduces appetite, slows digestion, and stimulates insulin release when b

Nausea? Hair loss? Headaches Acid reflux? Sulphur burps? These can be some of the most common side effects when using weight loss medications such as Mounjaro and Wegovy. We can help.

No, even though both contain semaglutide, they are licensed for different uses and come in different devices and doses. Doctors may...

Survey and trial follow-ups suggest people report higher satisfaction with Wegovy than older GLP-1 drugs, mainly because of greater...