In the early weeks, it’s common to notice reduced appetite and mild digestive effects such as nausea, bloating, or fatigue. These reactions usually improve as your body adjusts to the treatment and dose increases gradually. Keeping meals light, staying hydrated, and avoiding rich or spicy foods can make the transition smoother. Understanding your body’s early reactions NICE and NHS guidance describe the first month of Mounjaro treatment as a period of adjustment rather than r

Weight loss with Wegovy can lower blood pressure and improve metabolic markers, so clinicians often monitor and adjust existing treatments over time. If you use insulin or sulphonylureas for diabetes, doses may need review to reduce hypos as appetite and intake fall. Wegovy can slow stomach emptying, so timing may be adjusted for oral medicines that require predictable absorption. Always share a full medication list; Scotland and Wales follow similar clinical principles, thou

Yes — many services use Wegovy for maintenance when it remains clinically appropriate and well tolerated, but continuation depends on local commissioning rules. Some pathways set time limits or review benchmarks; others allow ongoing use if benefits and safety are clear. Whatever the policy, maintenance also relies on stable habits (protein, fibre, steps, simple strength work) so that stopping — if and when it happens — doesn’t trigger rapid regain. Scotland and Wales may fra

The effectiveness of Wegovy often feels strongest early on as appetite settles and “food noise” quietens, but the weight curve is rarely perfectly linear. Many people see quicker losses at first, followed by slower, steadier change as the body adapts and plateaus appear — that’s normal physiology, not failure. Services use review points to check technique, adherence, side effects, and whether your plan (protein, fibre, activity, sleep) matches the new appetite pattern. If pro

Intermittent use isn’t recommended; Wegovy is designed for consistent weekly dosing. Stopping and starting can bring appetite surges and weight regain, and it complicates review criteria. If you need a pause (side effects, procedures, travel), agree a plan with your clinician so re-starting is safe and structured. Why Wegovy is designed for steady use Wegovy (semaglutide) works best when injected on a consistent weekly schedule. NICE TA875 and NHS England’s 2025 weight-manage

Prioritise protein at each meal, slow down eating, and include fibre-rich foods to support fullness. Keep daily steps and two short resistance sessions weekly to protect strength; limit alcohol and maintain good sleep to stabilise appetite signals. Plan hydrated, portion-aware days around your injection, and rotate injection sites. Small, repeatable routines beat perfection — your team will help tailor these to your life, and devolved-nation services may offer slightly differ

Contact your clinic or GP well before the final dose in your pen so there’s time to process repeats and navigate any supply constraints....

No liquid is required — Wegovy is a subcutaneous injection, not a tablet. If you feel queasy, small sips of water or a ginger tea can...

Avoid stacking with another GLP-1 medicine unless advised by a specialist. If you use insulin or sulphonylureas, your prescriber may...

A typical schedule is once weekly stepping from 0.25 mg → 0.5 mg → 1.0 mg → 1.7 mg → 2.4 mg in staged intervals. The step-ups reduce stomach-related side effects and allow your routine to bed in. If symptoms persist, clinicians may extend a step or pause before moving on; some people remain at 1.7 mg if that’s the best balance of benefit and comfort. Follow the plan your service provides — don’t jump steps or compress intervals. Why dose escalation matters Wegovy (semaglutide

Anchor the injection to a weekly routine you never miss (e.g., Sunday evening after dinner) and set two phone reminders — one on the day,...

If a pen is lost, do not try to replace it with another GLP-1 medicine unless advised by a clinician. Contact your NHS clinic or pharmacy...

Many people find it helpful to set a phone reminder or calendar alert for their weekly dose. Writing the date of each injection on the...

Watch for persistent or worsening nausea, repeated vomiting, dizziness, or dehydration (very dark urine, feeling faint). Severe, constant...

No — Wegovy is intended as a single weekly dose. Splitting or repeating injections can upset the dosing schedule and increase side-effect...