Yes. You can change to a new weekly day as long as at least 3 full days have passed since your last injection. Once you switch, keep using the new day each week. If you’re unsure about the timing, ask your clinic to help you plan the change. Why flexibility exists Wegovy is designed as a once-weekly injection, and the dosing rules were created with real life in mind. Few people manage a routine that never changes. Work patterns, holidays, travel, or family events can all inte

Yes, trial evidence shows that Wegovy works best when combined with healthy eating and physical activity, leading to average weight losses of around 15%. Saxenda and Trulicity also perform better when paired with lifestyle support, but semaglutide at the doses used in Wegovy generally results in greater overall reductions. Why lifestyle support matters No weight-loss medicine is intended to work on its own. NICE guidance makes clear that drugs such as Wegovy, Saxenda, and Tru

There are no strict dietary restrictions, but simple tweaks help you feel better on treatment. Smaller portions, slower eating, and higher-protein meals reduce nausea and keep you fuller for longer. Early on, many people do better with lighter foods and by limiting very rich, spicy, or greasy dishes. Hydration matters — sip water regularly, and consider a little extra salt if you’ve cut back on processed foods and feel light-headed. Alcohol is best kept moderate, especially w

Energy levels often feel steadier as erratic snacking and large swings in intake settle down. Some people notice early fatigue during dose increases; this usually improves with better hydration, regular meals, and enough protein. If tiredness persists, your team can adjust the titration pace or check for other contributors such as low iron or not eating enough. What to expect in the first weeks Many people describe two parallel experiences at the start. On the one hand, appet

Wegovy alters appetite and satiety by activating GLP-1 receptors on neurons that signal “you’ve had enough,” while dialing down circuits that push “keep eating.” This reduces the intensity and frequency of cravings, especially for highly palatable foods. People often describe quieter “food noise,” easier portion control, and feeling satisfied sooner without forcing it. How GLP-1 receptors affect appetite Wegovy’s active ingredient, semaglutide, works by mimicking the hormone

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